One of the first human genetics departments in the country, the Department of Medical and Molecular Genetics at Indiana University (IU) School of Medicine has a rich history of training geneticists and genetic counselors and providing genetic consultation and counseling services. Currently ranked 5th in the nation among Genetics Departments for National Institutes of Health (NIH) Funding, received in 2023, the department contributes to the understanding of numerous genetic conditions through the integration of basic research in genetic and genomic mechanisms, translational research in disease models, and clinical trials in rare and common genetic diseases. Job Summary The Bioinformatics Analyst supports translational and basic science research by providing expertise in the analysis and interpretation of large-scale biological datasets. The position collaborates closely with faculty and trainees to design experiments, identify appropriate analytical approaches, interpret results, and support grant and manuscript preparation. Department-Specific Responsibilities Processes and analyzes next-generation sequencing (NGS) data, including bulk and single-cell RNA sequencing, DNA sequencing, epigenomics, spatial transcriptomics, metabolomics, and other high-throughput data types Develops, optimizes, and maintains bioinformatics pipelines Performs statistical and computational analyses Integrates multi-omics datasets Generates reports, visualizations, and summaries for investigators Contributes to the development of bioinformatics tools and databases Ensures reproducible research practices, maintains documentation, and provides consultation and training to researchers General Responsibilities Employs a variety of computational sequence analysis (mathematical and computing) tools to model and analyze biological data in support of researchers Accesses, extracts, and prepares data for analysis, including combining data run on multiple platforms as well as externally generated data in support of meta-analyses Installs, configures, customizes, and supports analytical software for data on research clusters Performs performance and reliability assessments to ensure systems are performing to maximum productivity and scientific validity Documents consultation, analysis, and quality control efforts Researches and stays up-to-date on emerging technologies/tools, trends, standards, and best practices related to bioinformatics Qualifications Combinations of related education and experience may be considered. Education beyond the minimum required may be substituted for work experience. Work experience beyond the minimum required may be substituted for education.
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